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Theme 2: Saving lives, optimising taxpayers` investment

Public Health England (PHE) uses models of vaccine-preventable diseases to inform (i) the Joint Committee on Vaccines and Immunisation decisions about new vaccine introductions and alterations to the existing schedule; (ii) vaccine procurement;  and (iii) making the public health and economic case for investment in robust vaccine programmes.  

The methodology for economic models is mature, thanks largely to innovative research over the last 20 years arising from a collaborative partnership between staff now at LSHTM and PHE. However, vaccine questions grow increasingly complex and need solutions that are transparent and acceptable to both policymakers and the public. 



  • Ensuring that new vaccines save lives and optimise taxpayers' investment 

  • Making existing vaccines more efficient 

  • Reducing antimicrobial resistance through vaccination 


To ensure vaccines provide value for money we will: 

  • develop mathematical and economic models for new vaccines 

  • examine whether vaccines can also prevent the development of resistant superbugs 

Lead researchers

Mark Jit

Professor of Vaccine Epidemiology

London School of Hygiene & Tropical Medicine